GS-441524 for FIP: Mechanism, Injection vs Oral Tablets & Standard Dosing by FIP Type
GS-441524 is the gold-standard antiviral medication proven to cure feline infectious peritonitis. As a nucleoside analog, it blocks viral RNA polymerase to stop mutated FIPV replication inside cats’ cells, eliminating the root of inflammation and organ damage.
Two Main Administration Forms for Home Treatment
Two mainstream administration forms are widely used in home treatment: injectable solution and oral tablets/capsules.
-
Injectable GS-441524: Higher bioavailability, stable blood concentration. Recommended priority for wet FIP, neurological and ocular FIP, cats refusing food or vomiting. Subcutaneous injection once daily, rotate injection sites to avoid skin irritation.
-
Oral GS-441524 Tablets: Lower stress for cats, suitable for mild dry FIP post acute recovery stage. Ideal for owners who cannot perform daily injections long-term.
Official Standard 84-Day (12-Week) Dosing Protocol
Official standard 84-day (12-week) full treatment course, dosage divided according to FIP severity:
-
Uncomplicated Wet FIP: 4–6mg/kg per day
-
Regular Dry FIP without nerve/eye damage: 6–8mg/kg per day
-
Ocular FIP (eye lesions only): 8mg/kg per day
-
Neurological FIP (seizure, ataxia, paralysis): 10mg/kg per day
Important Warning: Do not stop treatment early even if fever and appetite recover within 3–5 days. Premature discontinuation causes extremely high relapse risk. All dosage adjustments should follow professional veterinary guidance.